Drug & Alcohol Detox Services

Oxycodone Detox and Withdrawal

Oxycodone (oxycontin) is an opioid, a class of drugs commonly prescribed to help someone manage their pain levels—roughly 1.6 million people in the U.S. misuse opioids such as Oxy.

Suppose someone has been taking Oxycodone for over three weeks at an abusive dose (higher than recommended by the prescribing doctor). In that case, they will experience withdrawal symptoms when they stop taking it.

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Causes of Oxycodone Detox/Withdrawal

Many body systems are affected when someone stops taking Oxycodone. Withdrawal happens because it takes time for the body to adjust to the absence of opioids. 

Opioids can influence the body in the following ways: 

  • Affect the brainstem and central nervous system, which controls functions like breathing and heart rate, reducing breath rates that result in reduced heart rate. 
  • Act on the limbic system, which controls emotions, to produce feelings of pleasure or relaxation. 
  • Work to reduce pain signals to the brain via the spinal cord, which sends messages from the brain to the body, and vice versa

Prescription Opioid Withdrawal Symptoms 

Oxycodone detox is painful and can be potentially fatal if done improperly. Oxycodone withdrawal is often compared to bad cold or flu symptoms. 

There is a wide array of symptoms someone may experience when detoxing from prescription opioids such as Oxycodone, including: 

  • muscle aches
  • restlessness
  • excessive sweating
  • nausea and vomiting 
  • diarrhea and cramps
  • watery eyes and runny nose (flu-like)
  • excessive yawning 
  • anxiety and depression
  • agitation and irritability
  • inability to sleep 

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Oxycodone Detox Timeline

Although there is no set time for how long it takes to detox from Oxy, many people experience similar situations during the first week. 

Here is an example of week one Oxycodone detox timeline: 

Days 1 and 2: Withdrawal symptoms begin eight to 12 hours after the last dose. Initial symptoms can include joint pain, nausea, cravings, rapid breathing, runny nose and eyes, and excessive sweating. 

Days 3 to 5: This is when the worst symptoms often occur. Muscle aches are expected at this time, and nausea and vomiting are still present. Shaking and cramps are also possible. 

Days 6 and 7: People tend to start feeling a bit better physically now. However, as physical symptoms, slow psychological symptoms worsen. The end of withdrawal can lead to anxiety and depressed mood, in addition to remaining physical symptoms like nausea and diarrhea. 

Post the first week: Once Oxycodone has been detoxed from the body, it’s common for people to begin to feel guilt or remorse for things they did while abusing drugs. It is essential to seek proper mental healthcare to avoid drastic decisions or a return to drug abuse. 

How Long Does Oxycodone Withdrawal Take? 

Most people who go to a detox center will be put on a taper. The tapering process gradually reduces the amount of medication taken over the course of weeks. The amount of time this takes will vary by individual as it depends on how large the dose they start with is. 

Depending on the strength of Oxycodone and how long you’ve taken it, the detox process could take weeks or months to gradually and safely reduce the dose and remove it from the body. 

How long it takes to detox will depend on several factors, including: 

  • How often someone abuses Oxycodone.
  • The dose of Oxycodone consumed each time.
  • The amount of time someone has taken Oxy.
  • The mode of introduction (snorting, injecting, or ingesting a pill) 
  • If there is a co-occurring mental health disorder. 

Oxycodone Detox During Pregnancy

Opioid abuse during pregnancy can be dangerous to both mother and fetus. Babies born to people addicted to Oxycodone while pregnant will also experience withdrawal symptoms, including digestive issues, poor feeding, dehydration, vomiting, and potentially seizures. 

However, pregnant women mustn’t try to detox on their own, as this can result in the mother and fetus casualties. 

Medical Detox Programs: What to Expect

Oxycodone detox can come on quickly, and medical supervision is crucial during withdrawal. The typical detox program structure includes:

1. Initial medical screenings for incoming patients to address physical and mental health concerns. Blood tests measure the total amount of drugs in someone’s blood. These tests are then used to help develop individualized recovery plans.

A comprehensive medical, psychological, and drug history review ensures the patient receives the proper long-term addiction treatment. 

2. A combination of medications and behavioral therapies is used to stabilize the patient. The main goal of stabilization is to prevent any harm. In some cases, medications may be prescribed to reduce the severity of any withdrawal symptoms. 

3. Lastly, the detox program works to prepare patients for inpatient treatment. Because Oxycodone withdrawal symptoms can continue for an unknown amount of time, relapse is more likely to occur. Enrolling in an inpatient treatment program increases the chances of a continued successful recovery. 

Oxycodone Detox Risks and Fatalities

If someone chooses not to enroll in a treatment program after detox, they are much more likely to begin to use again. This is very dangerous because people will start abusing Oxy at the same dose they took before they detoxed. This can result in a fatal overdose after just one use. 

Questions about Oxycodone Detoxification

While choosing an Oxycodone detox program, it’s essential to consider the following questions: 

1. Are you abusing more than one substance?

When someone abuses a combination of drugs, the possible complications they can experience during detox will increase. To ensure you receive the proper treatment, it is essential to be upfront about all the substances you are taking. 

2. Do you also have a mental health disorder?

Many people tend to ignore treating the mental side of their addiction. Be mindful of your mental health going into a detox program. There will be many support systems built into treatment. But it is a crucial step to ensure a successful, long-term recovery. 

3. How severe is the Oxycodone use disorder?

It doesn’t take more than a few weeks to develop an Oxycodone use disorder, and it only builds in severity the more extended the abuse is. Individuals trying to quit a prescription painkiller will need to detox and follow up with another treatment type, such as inpatient or outpatient programs. 


Finding an Oxycodone Detox Program 

There are many options for Oxycodone detox programs available in the U.S. Opioids can be challenging to quit but not impossible. A Desert Rose Detox addiction specialist is ready to talk you through your next steps to living a life you love. Call us today at (844) 427-3509 or requesting information online.






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At Desert Rose, drug and alcohol detox is only the beginning. We offer a complete addiction treatment program here. Unlike most Florida rehabs, we feature all 5 primary ASAM levels of care you need within a single program.

Desert Rose Detox has earned Joint Commission Accreditation. We also enjoy membership in NAATP, state licensing and are associated with certified recovery residences (FARR).

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